The <i>Yersinia yop</i> regulon

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<jats:title>Summary</jats:title><jats:p>Growth of yersiniae is restricted at 37°C in the absence of calcium ions. This phenomenon correlates with the massive release of a set of proteins called Yops. Growth restriction and Yops production are governed by a 70 kb plasmid called pYV. <jats:italic>yop</jats:italic> genes are distributed throughout pYV and constitute a thermoactivated regulon controlled by the gene <jats:italic>virF</jats:italic>. The transcription activator VirF is a member of a new family of regulators including those of the arabinose and rhamnose operons as well as a regulator of enteric colonization pili. The role of calcium ions on the release of Yops remains largely unknown.</jats:p>

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