Randomized clinical trial of distal anastomotic interposition vein cuff in infrainguinal polytetrafluoroethylene bypass grafting
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- G D Griffiths
- Department of Vascular Surgery, Ninewells Hospital, Dundee DD1 9SY, UK
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- J Nagy
- Department of Vascular Surgery, Ninewells Hospital, Dundee DD1 9SY, UK
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- D Black
- Department of Vascular Surgery, Ninewells Hospital, Dundee DD1 9SY, UK
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- P A Stonebridge
- Department of Vascular Surgery, Ninewells Hospital, Dundee DD1 9SY, UK
抄録
<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>The aim was to examine the effect of a Miller vein cuff at the distal anastomosis on the medium- to long-term patency and limb salvage rates of femoral to above-knee and femoral to below-knee popliteal artery polytetrafluoroethylene (PTFE) bypasses.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>This study involved extended follow-up of the original cohort of patients included in a previously reported multicentre randomized clinical study. Outcome measures were bypass graft patency and limb salvage.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Two hundred and sixty-one bypass operations were originally randomized. For this study, full data were available on 235 (120 with a Miller cuff, 115 without). The cumulative 5-year patency rate for above-knee bypasses with a Miller cuff was 40 per cent, compared with 42 per cent for non-cuffed bypasses (P = 0·702). The cumulative 3-year patency rate for below-knee bypasses with a Miller cuff was 45 per cent, compared with 19 per cent for non-cuffed bypasses (P = 0·018). A Miller cuff had no significant effect on limb salvage for above-knee or below-knee bypasses.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Three-year patency rates of femoral to below-knee popliteal PTFE bypasses were improved by a Miller cuff. Miller cuffs had no effect on patency rates for femoral to above-knee popliteal bypasses at 5 years and did not improve limb salvage in either group.</jats:p> </jats:sec>
収録刊行物
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- British Journal of Surgery
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British Journal of Surgery 91 (5), 560-562, 2004-03-16
Oxford University Press (OUP)
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詳細情報 詳細情報について
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- CRID
- 1361699994455519872
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- NII論文ID
- 30014605511
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- DOI
- 10.1002/bjs.4501
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- ISSN
- 13652168
- 00071323
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