<scp>micro</scp>‐<scp>checker</scp>: software for identifying and correcting genotyping errors in microsatellite data
抄録
<jats:title>Abstract</jats:title><jats:p>DNA degradation, low DNA concentrations and primer‐site mutations may result in the incorrect assignment of microsatellite genotypes, potentially biasing population genetic analyses.<jats:sc>micro</jats:sc>‐<jats:sc>checker</jats:sc>is<jats:sc>windows</jats:sc>®‐based software that tests the genotyping of microsatellites from diploid populations. The program aids identification of genotyping errors due to nonamplified alleles (null alleles), short allele dominance (large allele dropout) and the scoring of stutter peaks, and also detects typographic errors.<jats:sc>micro</jats:sc>‐<jats:sc>checker</jats:sc>estimates the frequency of null alleles and, importantly, can adjust the allele and genotype frequencies of the amplified alleles, permitting their use in further population genetic analysis.<jats:sc>micro</jats:sc>‐<jats:sc>checker</jats:sc>can be freely downloaded from<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://www.microchecker.hull.ac.uk/">http://www.microchecker.hull.ac.uk/</jats:ext-link>.</jats:p>
収録刊行物
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- Molecular Ecology Notes
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Molecular Ecology Notes 4 (3), 535-538, 2004-06-08
Wiley
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詳細情報 詳細情報について
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- CRID
- 1362825895796071296
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- NII論文ID
- 30014966101
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- ISSN
- 14718286
- 14718278
- http://id.crossref.org/issn/14718278
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