The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations

  • Lawrence A. Loeb
    Department of Pathology, University of Washington, Seattle, WA 98195; and Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697
  • Douglas C. Wallace
    Department of Pathology, University of Washington, Seattle, WA 98195; and Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697
  • George M. Martin
    Department of Pathology, University of Washington, Seattle, WA 98195; and Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697

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