Clock Mutants of <i>Drosophila melanogaster</i>

  • Ronald J. Konopka
    Division of Biology, California Institute of Technology, Pasadena, Calif. 91109
  • Seymour Benzer
    Division of Biology, California Institute of Technology, Pasadena, Calif. 91109

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<jats:p>Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr. Both the eclosion rhythm of a population and the locomotor activity of individual flies are affected. All these mutations appear to involve the same functional gene on the X chromosome.</jats:p>

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