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- Richard W. Young
- From the Department of Anatomy, and the Jules Stein Eye Institute, University of California at Los Angeles School of Medicine, Los Angeles
抄録
<jats:p>The utilization of methionine-3H by retinal photoreceptor cells has been studied by radioautographic technique in the rat, mouse, and frog. In all three species, the labeled amino acid is concentrated initially in the inner segment of the cell. Within 24 hr, the radioactive material is displaced to the base of the outer segment, where it accumulates as a distinct reaction band. The reaction band then gradually moves along the outer segment and ultimately disappears at the apex of the cell, which is in contact with the retinal pigment epithelium. These findings are interpreted to indicate that the photoreceptor cell outer segment is continually renewed, by the repeated lamellar apposition of material (membranous discs) at the base of the outer segment, in conjunction with a balanced removal of material at its apex. The outer segment renewal rate is accelerated in frogs when ambient temperature is raised, and is elevated in both frogs and rats when the intensity of retinal illumination is increased.</jats:p>
収録刊行物
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- The Journal of Cell Biology
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The Journal of Cell Biology 33 (1), 61-72, 1967-04-01
Rockefeller University Press
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キーワード
詳細情報 詳細情報について
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- CRID
- 1360001114204653312
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- NII論文ID
- 30017402364
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- ISSN
- 15408140
- 00219525
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- データソース種別
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