Flexible Control of Mutual Inhibition: A Neural Model of Two-Interval Discrimination
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- Christian K. Machens
- Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
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- Ranulfo Romo
- Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
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- Carlos D. Brody
- Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
抄録
<jats:p>Networks adapt to environmental demands by switching between distinct dynamical behaviors. The activity of frontal-lobe neurons during two-interval discrimination tasks is an example of these adaptable dynamics. Subjects first perceive a stimulus, then hold it in working memory, and finally make a decision by comparing it with a second stimulus. We present a simple mutual-inhibition network model that captures all three task phases within a single framework. The model integrates both working memory and decision making because its dynamical properties are easily controlled without changing its connectivity. Mutual inhibition between nonlinear units is a useful design motif for networks that must display multiple behaviors.</jats:p>
収録刊行物
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- Science
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Science 307 (5712), 1121-1124, 2005-02-18
American Association for the Advancement of Science (AAAS)
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キーワード
詳細情報
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- CRID
- 1361699995714797696
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- NII論文ID
- 30020396504
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- ISSN
- 10959203
- 00368075
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- データソース種別
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- Crossref
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