Involvement of RNA in the Synthesis of Proteins

DOI Web Site 被引用文献2件
  • J. D. Watson
    Harvard Biological Laboratories, Cambridge, Massachusetts

書誌事項

タイトル別名
  • The ordered interaction of three classes of RNA controls the assembly of amino acids into proteins.

抄録

<jats:p>We can now have considerable confidence that the broad features of protein synthesis are understood. The involvement of RNA is very much more complicated than was imagined in 1953. There is not one functional RNA. Instead, protein synthesis demands the ordered interaction of three classes of RNA—ribosomal, soluble, and messenger. Many important questions, however, remain unanswered. For instance, there is no theoretical framework for the ribosomal subunits, nor for that matter, do we understand the functional significance of ribosomal RNA. Most satisfying is the realization that all the steps in protein replication will be shown to involve well-understood chemical forces. As yet we do not know all the details. For example, are the DNA base pairs involved in messenger RNA selection of the corresponding amino-acyl-sRNA? With luck, this will soon be known. We can thus have every expectation that future progress in understanding selective protein synthesis (and its consequences for embryology) will have a similarly well-defined and, when understood, easy-to-comprehend chemical basis.</jats:p>

収録刊行物

  • Science

    Science 140 (3562), 17-26, 1963-04-05

    American Association for the Advancement of Science (AAAS)

被引用文献 (2)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ