Brain Aluminum Distribution in Alzheimer's Disease and Experimental Neurofibrillary Degeneration

• D. R. Crapper

  Departments of Physiology and Medicine, University of Toronto, Toronto 5, Ontario, Canada

• S. S. Krishnan

  Departments of Physiology and Medicine, University of Toronto, and Center for Forensic Sciences, Toronto

• A. J. Dalton

  Department of Psychology, Mental Retardation Center, Toronto

抄録

Neurofibrillary degeneration is an important pathological finding in senile and presenile dementia of the Alzheimer type. Experimentally, aluminum induces neurofibrillary degeneration in neurons of higher mammals. Aluminum concentrations approaching those used experimentally have been found in some regions of the brains of patients with Alzheimer's disease.

収録刊行物

• Science

  Science 180 (4085), 511-513, 1973-05-04

  American Association for the Advancement of Science (AAAS)

キーワード

• Multidisciplinary

詳細情報

• CRID: 1360855568842010240
• NII論文ID: 30020503237
• DOI: 10.1126/science.180.4085.511
• ISSN: 10959203
• ISSN: 00368075
• ISSN: http://id.crossref.org/issn/00368075
• ISSN: http://id.crossref.org/issn/00068950
• Web Site: https://www.science.org/doi/pdf/10.1126/science.180.4085.511
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  • CiNii Articles