Viremia in Experimental Creutzfeldt-Jakob Disease

DOI Web Site 2 Citations
  • Elias E. Manuelidis
    Departments of Pathology and Neurology, Yale University School of Medicine, New Haven, Connecticut 06510
  • Edward J. Gorgacs
    Departments of Pathology and Neurology, Yale University School of Medicine, New Haven, Connecticut 06510
  • Laura Manuelidis
    Departments of Pathology and Neurology, Yale University School of Medicine, New Haven, Connecticut 06510

Abstract

<jats:p>Inoculation of the buffy coat of blood from guinea pigs infected with Creutzfeldt-Jakob disease resulted in passage of this disease to recipient animals. This demonstrates that there is a viremia in experimental Creutzfeldt-Jakob disease. These findings suggest that the hematogenous route may be implicated in the human infection and that the disease may possibly be transmitted by blood transfusions.</jats:p>

Journal

  • Science

    Science 200 (4345), 1069-1071, 1978-06-02

    American Association for the Advancement of Science (AAAS)

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