Cell Sensitivity to Gravity

DOI Web Site 8 Citations
  • A. Cogoli
    Laboratorium für Biochemie, Eidgenossische Technische Hochschule, CH-8092 Zurich, Switzerland
  • A. Tschopp
    Laboratorium für Biochemie, Eidgenossische Technische Hochschule, CH-8092 Zurich, Switzerland
  • P. Fuchs-Bislin
    Laboratorium für Biochemie, Eidgenossische Technische Hochschule, CH-8092 Zurich, Switzerland

Abstract

<jats:p> Cultures of human lymphocytes exposed in microgravity to the mitogen concanavalin A showed less than 3 percent of the activation of ground controls. This result supports the hypothesis, based on simulations at low <jats:italic>g</jats:italic> and experiments at high <jats:italic>g</jats:italic> , that microgravity depresses whereas high gravity enhances cell proliferation rates. The effects of gravity are particularly strong in cells undergoing differentiation. </jats:p>

Journal

  • Science

    Science 225 (4658), 228-230, 1984-07-13

    American Association for the Advancement of Science (AAAS)

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