Mechanisms of Memory

  • Larry R. Squire
    San Diego Veterans Administration Medical Center, San Diego, CA 92161, and University of California School of Medicine, La Jolla, CA 92093.

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<jats:p>Recent studies of animals with complex nervous systems, including humans and other primates, have improved our understanding of how the brain accomplishes learning and memory. Major themes of recent work include the locus of memory storage, the taxonomy of memory, the distinction between declarative and procedural knowledge, and the question of how memory changes with time, that is, the concepts of forgetting and consolidation. An important recent advance is the development of an animal model of human amnesia in the monkey. The animal model, together with newly available neuropathological information from a well-studied human patient, has permitted the identification of brain structures and connections involved in memory functions.</jats:p>

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  • Science

    Science 232 (4758), 1612-1619, 1986-06-27

    American Association for the Advancement of Science (AAAS)

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