New Lessons for Rotavirus Vaccines

  • Roger I. Glass
    R. I. Glass and J. R. Gentsch are in the Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
  • Jon R. Gentsch
    R. I. Glass and J. R. Gentsch are in the Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
  • Bernard Ivanoff
    B. Ivanoff is in the Vaccine Research and Development Division, Global Programme on Vaccines, World Health Organization, Geneva, Switzerland.

抄録

<jats:p> Rotavirus infects nearly all humans early in their lives and can sometimes prove dangerous or fatal. In his Perspective, Glass recounts the successes of first and second generation vaccines against rotaviruses. Nevertheless he believes that two papers in this week's issue [Ball <jats:italic>et al.</jats:italic> ( <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="101" related-article-type="in-this-issue" vol="272" xlink:href="10.1126/science.272.5258.101" xlink:type="simple">p. 101</jats:related-article> ) and Burns <jats:italic>et al.</jats:italic> ( <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="104" related-article-type="in-this-issue" vol="272" xlink:href="10.1126/science.272.5258.104" xlink:type="simple">p. 104</jats:related-article> )] illuminate aspects of the virulence of rotavirus and its susceptibility to immune attack that may guide the development of an even more effective third generation vaccine. </jats:p>

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  • Science

    Science 272 (5258), 46-46, 1996-04-05

    American Association for the Advancement of Science (AAAS)

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