Central Command Neurons of the Sympathetic Nervous System: Basis of the Fight-or-Flight Response

DOI Web Site 被引用文献21件
  • Arthur S. P. Jansen
    A. S. P. Jansen, X. V. Nguyen, V. Karpitskiy, A. D. Loewy, Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  • Xay Van Nguyen
    A. S. P. Jansen, X. V. Nguyen, V. Karpitskiy, A. D. Loewy, Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  • Vladimir Karpitskiy
    A. S. P. Jansen, X. V. Nguyen, V. Karpitskiy, A. D. Loewy, Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  • Thomas C. Mettenleiter
    T. C. Mettenleiter, Federal Research Centre for Virus Diseases of Animals, Friedrich-Loeffler Institutes, Institute of Molecular and Cellular Virology, D-17498 Insel Riems, Germany.
  • Arthur D. Loewy
    A. S. P. Jansen, X. V. Nguyen, V. Karpitskiy, A. D. Loewy, Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

抄録

<jats:p>During stress, the activity of the sympathetic nervous system is changed in a global fashion, leading to an increase in cardiovascular function and a release of adrenal catecholamines. This response is thought to be regulated by a common set of brain neurons that provide a dual input to the sympathetic preganglionic neurons regulating cardiac and adrenal medullary functions. By using a double-virus transneuronal labeling technique, the existence of such a set of central autonomic neurons in the hypothalamus and brainstem was demonstrated. These neurons innervate both of the sympathetic outflow systems and likely function in circumstances where parallel sympathetic processing occurs, such as in the fight-or-flight response.</jats:p>

収録刊行物

  • Science

    Science 270 (5236), 644-646, 1995-10-27

    American Association for the Advancement of Science (AAAS)

被引用文献 (21)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ