Coronary Flow Velocity Pattern Immediately After Percutaneous Coronary Intervention as a Predictor of Complications and In-Hospital Survival After Acute Myocardial Infarction

DOI Web Site 被引用文献12件
  • Atsushi Yamamuro
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Takashi Akasaka
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Koichi Tamita
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Kenji Yamabe
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Minako Katayama
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Tsutomu Takagi
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.
  • Shigefumi Morioka
    From the Division of Cardiology, Kobe General Hospital, Kobe, Japan, and Division of Cardiology, Kawasaki Medical School (T.A.), Kurashiki, Japan.

抄録

<jats:p> <jats:bold> <jats:italic>Background—</jats:italic> </jats:bold> Recently, it was reported that the degree of microvascular injury and left ventricular functional recovery during the chronic period can be predicted after treatment of the infarct-related artery based on the coronary flow velocity (CFV) pattern assessed using a Doppler guidewire. The aim of this prospective study was to examine whether the CFV pattern may predict complications and in-hospital survival after acute myocardial infarction (AMI). </jats:p> <jats:p> <jats:bold> <jats:italic>Methods and Results—</jats:italic> </jats:bold> The study population consisted of 169 consecutive patients with a first anterior AMI successfully treated with percutaneous coronary intervention (PCI). We examined the CFV pattern immediately after PCI using a Doppler guidewire. In accordance with previous findings, we defined severe microvascular injury as a diastolic deceleration time ≤600 ms and the presence of systolic flow reversal. Patients were divided into two groups: those without severe microvascular injury (n=118; group 1) and those with severe microvascular injury (n=51; group 2). All of the patients who had cardiac rupture were in group 2. Congestive heart failure (CHF) was observed more frequently in group 2 than in group 1 (53% versus 8%, <jats:italic>P</jats:italic> <0.001). The in-hospital cardiac mortality rate was significantly higher in group 2 than in group 1 (18% versus 0%, <jats:italic>P</jats:italic> <0.001). Nine patients in group 2 died, 5 patients because of CHF and 4 patients because of cardiac rupture. </jats:p> <jats:p> <jats:bold> <jats:italic>Conclusions—</jats:italic> </jats:bold> These findings suggest that the CFV pattern is an accurate predictor of the presence or absence of complications and of in-hospital survival after AMI. </jats:p>

収録刊行物

  • Circulation

    Circulation 106 (24), 3051-3056, 2002-12-10

    Ovid Technologies (Wolters Kluwer Health)

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