Eligibility for Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke

DOI Web Site 被引用文献5件
  • Dawn Kleindorfer
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Brett Kissela
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Alex Schneider
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Daniel Woo
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Jane Khoury
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Rosemary Miller
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Kathleen Alwell
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • James Gebel
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Jerzy Szaflarski
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Arthur Pancioli
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Edward Jauch
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Charles Moomaw
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Rakesh Shukla
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.
  • Joseph P. Broderick
    From the Department of Neurology (D.K., B.K., A.S., D.W., J.K., R.M., K.A., J.G., J.S., C.M., J.B.), University of Cincinnati College of Medicine, the Neuroscience Institute; Department of Emergency Medicine (A.P., E.J.), University of Cincinnati College of Medicine; and Department of Environmental Health (R.S.), University of Cincinnati, Cincinnati, Ohio.

書誌事項

タイトル別名
  • A Population-Based Study

抄録

<jats:p> <jats:bold> <jats:italic>Background and Purpose—</jats:italic> </jats:bold> Acute ischemic stroke patients are infrequently treated with recombinant tissue plasminogen activator (rtPA). We present unique population-based data regarding the eligibility of ischemic stroke patients for rtPA treatment. </jats:p> <jats:p> <jats:bold> <jats:italic>Methods—</jats:italic> </jats:bold> All ischemic strokes presenting to an emergency department (ED) within a biracial population of 1.3 million were identified. The patient was considered eligible for rtPA on the basis of exclusion criteria from the National Institute of Neurological Disorders and Stroke rtPA trial. </jats:p> <jats:p> <jats:bold> <jats:italic>Results—</jats:italic> </jats:bold> Of 2308 ischemic strokes, 1849 presented to an ED. Only 22% of all ischemic strokes in the population arrived in the ED in <3 hours from symptom onset; of these, 209 (51%) were ineligible for rtPA on the basis of mild stroke severity, medical and surgical history, or blood tests. </jats:p> <jats:p> <jats:bold> <jats:italic>Conclusions—</jats:italic> </jats:bold> In our population in 1993 to 1994, 8% of all ischemic stroke patients presented to an ED within 3 hours and met other eligibility criteria for rtPA. Even if time were not an exclusion for rtPA, only 29% of all ischemic strokes in our population would have otherwise been eligible for rtPA. </jats:p>

収録刊行物

  • Stroke

    Stroke 35 (2), e27-, 2004-02

    Ovid Technologies (Wolters Kluwer Health)

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