An epidemiologic study of herpes simplex virus type 1 and 2 infection in Japan based on type-specific serological assays

• M. HASHIDO

• F. K. LEE

• A. J. NAHMIAS

• H. TSUGAMI

• S. ISOMURA

• Y. NAGATA

• S. SONODA

• T. KAWANA

抄録

A seroepidemiologic study of herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) was performed on Japanese adults. Serum samples collected between 1985–9 from a total of 536 healthy adults, female prostitutes, males with sexually transmitted diseases (STD), homosexual men, and pregnant women were studied by immunodot assays using HSV type-specific antigens, glycoproteins G (gG1 and gG2). HSV-1 infections correlated mostly with age and was widely prevalent among subjects <40 years. HSV-2 prevalence varied greatly among subgroups defined by sexual activity and was associated with risk behaviours for prostitution, infection with STD, and homosexual activity. HSV-2 seroprevalence was highest among prostitutes (80%), lowest among pregnant women (7 %), and intermediate in STD patients (23%) and homosexuals (24%). Because HSV-1 infection during childhood has been decreasing, primary genital HSV-2 infection, with its higher frequency of clinical manifestations, will become a greater burden to the public health in Japan.

収録刊行物

• Epidemiology and Infection

  Epidemiology and Infection 120 (2), 179-186, 1998-03

  Cambridge University Press (CUP)

キーワード

• Infectious Diseases
• Epidemiology

詳細情報

• CRID: 1361981469609261184
• NII論文ID: 30022866743
• DOI: 10.1017/s095026889700856x
• ISSN: 14694409
• ISSN: 09502688
• ISSN: http://id.crossref.org/issn/09502688
• Web Site: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S095026889700856X
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