抄録
<jats:title>Abstract</jats:title><jats:p>A case‐control study was performed to estimate the relative risk of developing prostate cancer for men with a positive family history. Extensive cancer pedigrees were obtained on 691 men with prostate cancer and 640 spouse controls.</jats:p><jats:p>Fifteen percent of the cases but only 8% of the controls had a father or brother affected with prostate cancer (<jats:italic>P</jats:italic> < .001). Men with a father or brother affected were twice as likely to develop prostate cancer as men with no relatives affected. In addition, there was a trend of increasing risk with increasing number of affected family members such that men with two or three first degree relatives affected had a five and 11–fold increased risk of developing prostate cancer.</jats:p><jats:p>Recognizing that 9–10% of U.S. men will develop prostate cancer in their lifetime, men with a family history of prostate cancer should be advised of their significantly increased prostate cancer risk and should undergo appropriate screening measures for this disease.</jats:p>
収録刊行物
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- The Prostate
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The Prostate 17 (4), 337-347, 1990-01
Wiley
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詳細情報 詳細情報について
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- CRID
- 1362262944009067392
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- NII論文ID
- 30025838987
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- ISSN
- 10970045
- 02704137
- http://id.crossref.org/issn/02704137
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- データソース種別
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- Crossref
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