A multivariate analysis of clinical and pathological variables in prognosis after resection of large bowel cancer

  • P H Chapuis
    Colorectal Cancer Project, Concord Hospital, Sydney, Australia
  • O F Dent
    Faculty of Arts, The Australian National University, Canberra, Australia
  • R Fisher
    New South Wales State Cancer Council, Sydney, Australia
  • R C Newland
    Colorectal Cancer Project, Concord Hospital, Sydney, Australia
  • M T Pheils
    Colorectal Cancer Project, Concord Hospital, Sydney, Australia
  • E Smyth
    Colorectal Cancer Project, Concord Hospital, Sydney, Australia
  • Kim Colquhoun
    Colorectal Cancer Project, Concord Hospital, Sydney, Australia

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<jats:title>Abstract</jats:title> <jats:p>Data on 709 patients who had a resection for colorectal carcinoma at Concord Hospital between 1971 and 1980 were studied to determine the independent effects on survival of several patient characteristics and pathological variables using the Cox regression model. Clinicopathological stage had the strongest association. Other variables ranked according to their relative importance independent of stage were: histological grade, level of direct spread, the presence of venous invasion, age and sex of the patient and the presence of obstruction.</jats:p>

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