Prevalence of Carotid Atherosclerosis in Diabetic Patients Ultrasound high-resolution B-mode imaging on carotid arteries

  • Ryuzo Kawamori
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Yamasaki Yamasaki
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Hiroyuki Matsushima
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Hideko Nishizawa
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Katsunori Nao
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Hougaku Hougaku
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Hiroaki Maeda
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Nobuo Handa
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Masayasu Matsumoto
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan
  • Takenobu Kamada
    First Department of Medicine, Osaka University Medical School 1-1-50 Fukushima, Fukushima-Ku, Osaka, Japan

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<jats:sec> <jats:title>OBJECTIVE</jats:title> <jats:p>To quantitatively assess atherosclerosis of the carotid artery in subjects with and without diabetes.</jats:p> </jats:sec> <jats:sec> <jats:title>RESEARCH DESIGN AND METHODS</jats:title> <jats:p>Ultrasound high resolution B-mode imaging of carotid arteries was conducted on 71 nondiabetic subjects without hyperlipidemia or hypertension and 295 diabetic patients to determine IMT of the arterial wall.</jats:p> </jats:sec> <jats:sec> <jats:title>RESULTS</jats:title> <jats:p>IMT was linearly related with age in nondiabetic (IMT = [0.0087 × age] + 0.3318) and diabetic subjects (IMT = [0.0155 × age] + 0.32450). The regression coefficient for age was significantly greater in diabetic than nondiabetic subjects. IMT (mean ± SD) of diabetic subjects aged 20–29 was significantly &gt; that of nondiabetic subjects aged 20–29 (0.73 ± 0.27 vs. 0.52 ± 0.07 mm, P &lt; 0.01). Multivariate regression analysis of 275 NIDDM patients indicated smoking, hyperlipidemia, duration of diabetes, hypertension, and age were factors determining thickness of the carotid arterial wall.</jats:p> </jats:sec> <jats:sec> <jats:title>CONCLUSIONS</jats:title> <jats:p>Diabetes, along with age, hyperlipidemia, smoking, and hypertension, aggravates carotid atherosclerosis.</jats:p> </jats:sec>

収録刊行物

  • Diabetes Care

    Diabetes Care 15 (10), 1290-1294, 1992-10-01

    American Diabetes Association

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