The Value of Cardiovascular Autonomic Function Tests: 10 Years Experience in Diabetes

DOI PDF 被引用文献16件
  • David J Ewing
    University Department of Medicine and Diabetic Department Royal Infirmary, Edinburgh, Scotland
  • Christopher N Martyn
    University Department of Medicine and Diabetic Department Royal Infirmary, Edinburgh, Scotland
  • Robert J Young
    University Department of Medicine and Diabetic Department Royal Infirmary, Edinburgh, Scotland
  • Basil F Clarke
    University Department of Medicine and Diabetic Department Royal Infirmary, Edinburgh, Scotland

抄録

<jats:p>Five simple, noninvasive cardiovascular reflex tests have been used to assess autonomic function in one center over the past 10 yr. Seven hundred seventy-four diabetic subjects were tested for diagnostic and research purposes. In 543 subjects completing all five tests, abnormalities of heart rate tests occurred in 40%, while abnormal blood pressure tests occurred in &lt; 20%. Their results were grouped as normal (39%), early (15%), definite (18%), and severe (22%) involvement. Six percent had an atypical pattern of results. Two hundred thirty-seven diabetic subjects had the tests repeated ≤3 mo apart: 26% worsened, 71% were unchanged, and only 3% improved. The worsening followed a sequential pattern with first heart rate and later additional blood pressure abnormalities. Comparison between a single test (heart rate response to deep breathing) and the full battery in 360 subjects showed that one test alone does not distinguish the degree or severity of autonomic damage. These tests provide a useful framework to assess autonomic neuropathy simply, quickly, and noninvasively.</jats:p>

収録刊行物

  • Diabetes Care

    Diabetes Care 8 (5), 491-498, 1985-09-01

    American Diabetes Association

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