Histiocytoid breast carcinoma: an apocrine variant of lobular carcinoma

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<jats:p>Two cases of <jats:italic>in situ</jats:italic> and invasive histiocytoid breast carcinoma are described. The invasive components of both tumours showed architectural and cytological similarities to lobular carcinoma. The <jats:italic>in situ</jats:italic> components showed areas of classical lobular carcinoma <jats:italic>in situ</jats:italic>, areas of lobular carcinoma with apocrine features and areas with transitional features. It is concluded that histiocytoid carcinoma represents an apocrine variant of lobular carcinoma. Differentiation of this tumour from chronic sclerosing inflammation may be difficult in both primary and secondary lesions.</jats:p>

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