Cetirizine treatment of allergic cough in children with pollen allergy

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<jats:p>Cetirizine, an antihistamine widely used in the treatment of allergic rhinoconjunctivitis, also has antiallergic activity. The present study aimed to evaluate cetirizine as a treatment for children with allergic cough due to pollen allergy. This was a parallel‐group, double‐blind, placebo‐controlled, randomized study. Twenty children with pollinosis were enrolled: they were subdivided into two groups receiving a 1‐month treatment during the pollen season. The following variables were monitored: 1) clinical symptoms and respiratory data (spirometry and PEF) evaluated at baseline and at the end of the study by allergists and by a daily diary card, and 2) pollen count. This study shows that cetirizine treatment reduces cough intensity (<jats:italic>P</jats:italic> < 0.05) and frequency (<jats:italic>p</jats:italic> < 0.01). In conclusion, cetirizine does clinically improve cough due to pollen allergy.</jats:p>

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  • Allergy

    Allergy 52 (7), 752-754, 1997-07

    Wiley

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