Hematological and Pressor Hormone Responses to Mental Stress in Essential Hypertensive Patients: A Comparison with Isometric Handgrip Exercise.

• Sakamoto Hironosuke

  Second Department of Internal Medicine Gunma University School of Medicine

• Imataka Kouji

  Institute for Adult Diseases, Asahi Life Foundation

• Nishimura Hiroshi

  Third Department of Internal Medicine, Faculty of Medicine University of Tokyo

• Fujii Jun

  Institute for Adult Diseases, Asahi Life Foundation

抄録

We carried out both mental stress (MS) and isometric handgrip exercise (IHG) tests in 20 mild hypertensive patients to compare responses of blood pressure, heart rate, blood cell count and pressor hormones between the two tests. Increments of blood pressure and heart rate by MS (mean±SEM, 42± 2/17±1mmHg and 8±1beats/mm) were similar to those by IHG (39 ±3/17±2mmHg and 6±1beats/ min). Packed cell volume, erythrocytes, leukocytes, and platelets significantly increased in the MS test (1.3±0.3%, 1.7±0.3%, 10.3±2.1% and 2.8±1.6%, respectively) and in the IHG test (1.3±0.3%, 1.0 ±0.3%, 6.2±1.2% and 1.9±0.8% respectively). In both tests the percent increase was significantly greater in leukocytes than in erythrocytes and platelets (p<0.01). A comparison between the two tests revealed that the increase in leukocyte count was significantly greater in the MS than in the IHG test (p <0.05). Plasma noradrenaline, adrenaline and vasopressin levels significantly increased in both tests and there were no significant differences in responses of these pressor hormones between the two tests. Plasma active renin and aldosterone levels significantly increased in the MS test, but remained unchanged in the IHG test. Although the responses to both stressors are mainly induced by the sympathoadrenal excitation, there are some differences in details between the two tests. We concluded that MS induced a greater increase in leukocyte count than IHG with equipressor response and activated the renin-angiotensin-aldosterone system, which was not stimulated by the latter. (Hypertens Res 1992; 15: 33-39)

収録刊行物

• Hypertension Research

  Hypertension Research 15 (1), 33-39, 1992

  日本高血圧学会

キーワード

• hypertension
• mental stress
• handgrip
• leukocyte
• renin

詳細情報

• CRID: 1390282679697002496
• NII論文ID: 130003456118
• NII論文ID: 30034931556
• NII書誌ID: AA10847079
• DOI: 10.1291/hypres.15.33
• ISSN: 13484214
• ISSN: 09169636
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可