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- OHKOHCHI NOBUHIRO
- The Second Department of Surgery, Tohoku University School of Medicine
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- SASAKI TAKASHI
- The Second Department of Surgery, Tohoku University School of Medicine
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- NAMIKI KENJI
- The Second Department of Surgery, Tohoku University School of Medicine
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- KATOH HIROTAKA
- The Second Department of Surgery, Tohoku University School of Medicine
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- KOIZUMI MASANORI
- The Second Department of Surgery, Tohoku University School of Medicine
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- TAGUCHI YOSHIO
- The Second Department of Surgery, Tohoku University School of Medicine
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- FUJIMOTO HIDEE
- the Department of Clinical and Laboratory Medicine, Tohoku University School of Medicine
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- ENDO EIKO
- the Department of Clinical and Laboratory Medicine, Tohoku University School of Medicine
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- KASAI MORIO
- The Second Department of Surgery, Tohoku University School of Medicine
抄録
OHKOHCHI, N., SASAKI, T., NAMIKI, K., KATOH, H., KOIZUMI, M., TAGUCHI, Y., FUJIMOTO, H., ENDO, E. and KASAI, M. Liver transplantation in Dogs after 30 Minutes of Warm Ischemia. Tohoku J. exp. Med., 1986, 148 (3), 285-294 - In order to investigate the applicability of liver transplantation after warm ischemia, a partial auxiliary auto-transplantation of the liver after 30min of warm ischemia was carried out in 9 mongrel dogs. Among them, 6 dogs survived longer than 7 days. Liver functions, blood coagulability and histological changes were investigated before and after the transplantation. Serum GOT, LDH, and OPT levels were elevated immediately after transplantation, and returned to normal within a few days. Hemostatic tests also showed significant abnormalities after transplantation. Although PT and thrombotest became normal within a week, PTT and antithrombin III remained slightly abnormal for longer periods. Microscopically, vacuolization and degeneration of hepatocytes were observed after transplantation but they recovered completely within 4 weeks. Based on these results, it could be said that the livers subjected to warm ischemia for 30min ischemia were still acceptable for auxiliary transplantation.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 148 (3), 285-294, 1986
東北ジャーナル刊行会