Characterization of spontaneous fosfomycin (phosphonomycin)-resistant cells of Escherichia coli B in vitro.

• TSURUOKA TSUTOMU

  Meiji Seika Kaisha, Ltd., Research Laboratories

• YAMADA YUJIRO

  Meiji Seika Kaisha, Ltd., Research Laboratories

書誌事項

タイトル別名

• Characterization of spontaneous fosfomy
• (PHOSPHONOMYCIN)-RESISTANT CELLS OF <i>ESCHERICHIA COLI</i> B <i>IN VITRO</i>

抄録

The characteristics of spontaneous fosfomycin-resistant cells isolated in vitro were investigated. Distribution of resistance level to the drug in Escherichia coli B was thought to be broad and, for this reason, resistance to the drug seemed to develope easily in vitro.In the process of isolating the resistant cells, two groups of cells, differing in colony size, were distinguished. Smaller colony-forming cells appeared more frequently than Larger colony-forming ones. Many of the former seemed to be slow growers and decreased simultaneously in utilization of several carbohydrates. One of the Smaller colony-forming isolates was distinctly different from glp T^- or uhp^-.

収録刊行物

• The Journal of Antibiotics

  The Journal of Antibiotics 28 (11), 906-911, 1975

  公益財団法人 日本感染症医薬品協会

キーワード

• Drug Discovery
• Pharmacology

詳細情報

• CRID: 1390282679127024256
• NII論文ID: 130003498951
• NII論文ID: 40005314090
• NII書誌ID: AA0069330X
• DOI: 10.7164/antibiotics.28.906
• COI: 1:CAS:528:DyaE28XhtVahsrY%3D
• ISSN: 18811469
• ISSN: 00218820
• ISSN: http://id.crossref.org/issn/00218820
• NDL書誌ID: 1629836
• PubMed: 1104551
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I1629836
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可