Effects of Oral Care on Development of Oral Mucositis and Microorganisms in Patients with Esophageal Cancer
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- Yoneda Saori
- Department of Gerodontology, Graduate School, Tokyo Medical and Dental University, Japan Department of Bacteriology I, National Institute of Infectious Diseases, Japan
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- Imai Susumu
- Department of Oral Health, National Institute of Public Health, Japan
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- Hanada Nobuhiro
- Department of Oral Health, National Institute of Public Health, Japan
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- Yamazaki Tsuneyoshi
- Section of Dentistry for Persons with Disabilities, Graduate School, Tokyo Medical and Dental University, Japan
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- Senpuku Hidenobu
- Department of Bacteriology I, National Institute of Infectious Diseases, Japan
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- Ota Yojiro
- Department of Oral Surgery, Shizuoka Cancer Center, Japan
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- Uematsu Hiroshi
- Department of Gerodontology, Graduate School, Tokyo Medical and Dental University, Japan
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<p>We evaluated the effects of special oral care using a toothbrush with combined irrigation and suctioning functions, along with povidone-iodine to treat oral bacteria and mucositis, in esophageal cancer patients undergoing chemoradiotherapy. In the special care group, oral hygiene was performed 3 days a week after dinner. Bacteria in saliva and plague samples were measured at various sampling points after chemoradiotherapy. The incidence of mucositis was significantly reduced in the special care group in comparison with the control group. Total streptococci were significantly decreased in the opportunistic pathogens-positive and lower-level mutans streptococci control group during chemoradiotherapy, but they were not reduced in the opportunistic pathogens-negative and higher-level mutans streptococci control groups or in the special care group. Our results showed that a special oral care regimen enabled the total population of streptococci microflora to remain stable, was negatively correlated with opportunistic pathogens and positively correlated with mutans streptococci infection, and prevented the development of mucositis.</p>
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 60 (1), 23-28, 2007-02-28
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詳細情報 詳細情報について
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- CRID
- 1390861936166963968
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- NII論文ID
- 40015274068
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 8656892
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可