子宮頸癌の原発巣,旁結合織の炎症並に所属リンパ節の洞カタルについて

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  • Studies on Inflammatory Process in Carcinoma of the Uterine Cervix, with a Special Reference to the Original Foci, Parametrium and Sinus Catarrh of Regional Lymph Nodes
  • シキュウケイガン ノ ゲンパツ ソウ , ホウケツゴウショク ノ エンショウ ナラビニ ショゾク リンパセツ ノ ホラ カタル ニ ツイテ

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Since Imai advocated the C. P. L. classification in 1949, other investigators confirmed it to be adequate in their follow-up studies, thus re-affirming the significance of the role played by the interstitium in carcinoma of the uterine cervix.<br>In the present series of research the author studied the inflammatory processes of the original focus in the interstitium and in the parametrium and the sinus catarrh in the regional lymph nodes, in 50 cases of carcinoma of the uterine cervix obtained by the Okabayshi Operation (with pelvic lymphadenectomry extentended abdominal hysterectomy) and in 50 cases selected as the control group given X-ray irradiation six times (surface dose of 1, 800 r) before the same operation, all treated in the clinic of the Departmant of Obstetrics and Gynecology, Okayana University Medical School during the period from August 1956 to May 1958; and obtained the following results:<br>By dividing these cases according to the C. P. L. classification (Imai), Nagase's classification, clinical stages, the growth patterns of the original focus, and the grades of the inflammatory processes of the original focus, it has been found that those whose inflammatory reaction of the original focus is strong, the inflammation of the parametrium is weaker, showing a inverse mutual relationship between the two; and in addition, that those whose inflammatory reaction of the original focus is stronger, their prognosis is better. Morever, it has been demonstrated that the histological finding of inflammatory lesion does not necessarily coincide with the detection of bacilli. Therefore, the author is of the opinion, the same as claimed by Imai et al., that the anti-cancer factor in vivo seems to exist for the inflammtion.<br>Still further, no finding worthy of any special mention can be recognized in lymph nodes.<br>Furthermoer, an approximately similar relationship as observed in the experimental group has been found inthe control as well.

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