大動脈，左主気管支に浸潤した高度進行胸部食道癌に対し，weekly DOC＋ low-dose FP 療法が奏功し根治切除し得た一例

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  • ショウレイ ホウコク ダイドウミャク サシュ キカンシ ニ シンジュン シタ コウド シンコウ キョウブ ショクドウガン ニ タイシ weekly DOC low dose FP リョウホウ ガ ソウコウ シ コンジ セツジョ シエタ イチレイ
  • A case of advanced esophageal carcinoma patient with invasion to aorta and left main bronchus who underwent curative esophagectomy after response to docetaxel,5‐FU and cisplatin combination therapy
  • ダイドウミャク サシュキカンシ ニ シンジュン シタ コウド シンコウ キョウブ ショクドウガン ニ タイシ weekly DOC＋ low-dose FP リョウホウ ガ ソウコウシ コンチ セツジョ シエタ イチレイ

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A ７０s woman was pointed out lower thoracic advanced esophageal squamous cell carcinoma with a chief complaint of dysphagia by upper gastrointestinal endoscopy. Computed tomography （CT）revealed that original tumor invaded to aorta and left main bronchus. Weekly docetaxel plus low-dose ５-FU and cisplatin therapy decreased the tumor. The invasion to aorta and left main bronchus was disappeared. She underwent curative esophagectomy. Main tumor had wide adherence to left main bronchus and aorta but was able to be resected. She underwent subtotal esophagectomy and gastric tube reconstruction by retrosternal route. Pathological diagnosis revealed carcinoma invaded from submucosa to adventitia and deep margin was negative（pT３）. Advanced esophageal carcinoma with invasion to aorta and main bronchus is commonly treated by definitive chemoradiotherapy and hardly undergo curative resection. This case underwent curative resection after only chemotherapy. This case suggests excellent anticancer effect of the triple drug therapy.

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