Investigation of Innovative Synthesis of Biologically Active Compounds on the Basis of Newly Developed Reactions
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- Honda Toshio
- Faculty of Pharmaceutical Sciences, Hoshi University
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Synthesis of biologically active compounds, including natural products and pharmaceutical agents, is an important and interesting research area since the large structural diversity and complexity of bioactive compounds make them an important source of leads and scaffolds in drug discovery and development. Many structurally and also biologically interesting compounds, including marine natural products, have been isolated from nature and have also been prepared on the basis of a computational design for the purpose of developing medicinal chemistry. In order to obtain a wide variety of derivatives of biologically active compounds from the viewpoint of medicinal chemistry, it is essential to establish efficient synthetic procedures for desired targets. Newly developed reactions should also be used for efficient synthesis of desired compounds. Thus, recent progress in the synthesis of biologically active compounds by focusing on the development of new reactions is summarized in this review article.
収録刊行物
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- CHEMICAL & PHARMACEUTICAL BULLETIN
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CHEMICAL & PHARMACEUTICAL BULLETIN 60 (6), 687-705, 2012
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679155219712
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- NII論文ID
- 130001852468
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- NII書誌ID
- AA00602100
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- COI
- 1:STN:280:DC%2BC38jgvFakug%3D%3D
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- ISSN
- 13475223
- 00092363
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- NDL書誌ID
- 023665849
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- PubMed
- 22689419
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可