Simulation for a Real-time Positioning System for Radiotherapy Based on Annihilation Gamma-rays' Detection from a Radiopharmaceutical Concentrated Tumor

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To improve radiosurgery for tumors with motion, such as those of lung cancer, a real-time positioning system based on annihilation gamma-ray detection from a radiopharmaceutically concentrated tumor was evaluated using simulations. Several examinations related to the collimator shape were conducted. A pair of wedge-type collimators had good balance in detection efficiency and position sensitivity. As an example of the simulation, a 6 mm shift of a lung tumor of 5 cm diameter was detectable with accuracy of 2 sigma using two pairs of detectors, of which the sizes were 20×70 mm.

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