三重県で発症した野生動物肉摂食歴のない4型E型肝炎ウイルス愛知静岡株による急性E型肝炎の1例

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タイトル別名
  • A case of acute hepatitis E in Mie prefecture infected with genotype 4 hepatitis E virus strain endemic in Aichi and Shizuoka prefectures (Aichi/Shizuoka strain), without a history of eating wild animal meat
  • ミエケン デ ハッショウ シタ ヤセイ ドウブツニク セッショクレキ ノ ナイ 4ガタ Eガタ カンエンウイルス アイチ シズオカカブ ニ ヨル キュウセイ Eガタ カンエン ノ 1レイ

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We experienced a case of hepatitis E in Mie prefecture infected with genotype 4 hepatitis E virus (HEV) strain endemic in Aichi and Shizuoka prefectures (Aichi/Shizuoka strain). The HEV isolate obtained from the patient clustered with other Aichi/Shizuoka strains with 100% of bootstrap value in the phylogenetic tree, and was more than 97.8% identical to other Aichi/Shizuoka strains, in the 412-nucleotide sequence within the ORF2 region. Interestingly, the patient had no history of consuming wild animal meat although all other reported Aichi/Shizuoka strains were recovered from meat from wild animals or humans after eating wild animal meat. The finding indicated that the origin of Aichi/Shizuoka strains is confined not only to wild animal meat but also to other unknown reservoirs.

収録刊行物

  • 肝臓

    肝臓 55 (7), 405-408, 2014

    一般社団法人　日本肝臓学会

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