Toxicity Assessment of Fe-Mn-Al Ternary Alloys Using a Probit Dose-Response Model and an Augmented Simplex Design

• Chang Shih-Hang

  Department of Chemical and Materials Engineering, National I-Lan University

• Chen Bor-Yann

  Department of Chemical and Materials Engineering, National I-Lan University

• Chiang Chin-He

  Department of Chemical and Materials Engineering, National I-Lan University

Abstract

This study establishes a toxicity assessment of the mixture of Fe³⁺, Mn²⁺, and Al³⁺ ions by employing a Probit dose-response model and an augmented simplex design. The toxicity of individual Fe³⁺, Mn²⁺, and Al³⁺ metal ions with respect to Escherichia coli DH5α is in the order of Mn²⁺ > Fe³⁺ > Al³⁺. The mixture of Fe³⁺, Mn²⁺, and Al³⁺ ions shows a hump region and a saddle region in the IC₅₀ values contour plot. Fe-Mn-Al ternary alloys may possess a lower toxic risk when the ratio of released metal ions approaches the hump region of the contour plot. Fe-Mn-Al ternary alloys may present an increased toxic risk when the ratio of released metal ions gets close to the saddle regions of the contour plot.

Journal

• MATERIALS TRANSACTIONS

  MATERIALS TRANSACTIONS 56 (1), 135-139, 2015

  The Japan Institute of Metals and Materials

Keywords

• iron-manganese-aluminum alloys
• toxicity assessment
• augmented simplex design
• probit dose-response

Details

• CRID: 1390282679230364160
• NII Article ID: 130004825237
• NII Book ID: AA1151294X
• DOI: 10.2320/matertrans.m2014108
• ISSN: 13475320
• ISSN: 13459678
• NDL BIB ID: 026014188
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026014188
• Web Site: https://www.jstage.jst.go.jp/article/matertrans/56/1/56_M2014108/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed