頭頸部骨軟部肉腫13例の検討

  • 安慶名 信也
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 上原 貴行
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 山下 懐
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 又吉 宣
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 長谷川 昌宏
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 真栄田 裕行
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座
  • 鈴木 幹男
    琉球大学大学院医学研究科耳鼻咽喉・頭頸部外科学講座

書誌事項

タイトル別名
  • A Study on 13 Cases of Bone and Soft Tissue Sarcomas in the Head and Neck
  • アタマ ケイブコツナンブ ニクシュ 13レイ ノ ケントウ

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抄録

Since bone and soft tissue sarcomas arising from the head and neck region are very rare, the standard treatment protocol has yet to be established. In the present study, 13 cases with bone and soft tissue sarcomas treated from 2007 to 2014 were analyzed. The mean period from initial visit to final pathological diagnosis was approximately 3 weeks, and 38.5% of the cases needed several biopsies for an accurate diagnosis. Death occurred early for those cases in which more than 40 days was needed to obtain the histological diagnosis. The 3-year overall survival in 13 cases was 35.2%. As the cause of death was uncontrolled local lesion, the locoregional control was more important than distant metastasis control for the prognosis. Tumor location, TNM stage, and histological grade affected the prognosis of the sarcomas. Radiation therapy including heavy ion and proton beam radiotherapy was not so effective as the primary treatment, as was the case with salvage treatment of sarcomas in the head and neck. Although the primary treatment of sarcomas was surgical treatment with an adequate margin, an efficient treatment protocol should be established to obtain a better prognosis.

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