FOCUS REVIEWS ON IMAGING : Early Detection of Vulnerable Atherosclerotic Plaque for Risk Reduction of Acute Aortic Rupture and Thromboemboli and Atheroemboli Using Non-Obstructive Angioscopy
-
- Komatsu Sei
- Cardiovascular Center, Amagasaki Central Hospital
-
- Ohara Tomoki
- Cardiovascular Center, Amagasaki Central Hospital
-
- Takahashi Satoru
- Cardiovascular Center, Amagasaki Central Hospital
-
- Takewa Mitsuhiko
- Cardiovascular Center, Amagasaki Central Hospital
-
- Minamiguchi Hitoshi
- Cardiovascular Center, Amagasaki Central Hospital Department of Cardiology, Osaka University School of Medicine
-
- Imai Atsuko
- Cardiovascular Center, Amagasaki Central Hospital Department of Cardiology, Osaka University School of Medicine
-
- Kobayashi Yasuhiko
- Cardiovascular Center, Amagasaki Central Hospital
-
- Iwa Nobuzo
- Department of Pathology, Amagasaki Central Hospital
-
- Yutani Chikao
- Department of Pathology, Amagasaki Central Hospital
-
- Hirayama Atsushi
- Department of Cardiology, Nihon University School of Medicine
-
- Kodama Kazuhisa
- Cardiovascular Center, Amagasaki Central Hospital
書誌事項
- タイトル別名
-
- Early Detection of Vulnerable Atherosclerotic Plaque for Risk Reduction of Acute Aortic Rupture and Thromboemboli and Atheroemboli Using Non-Obstructive Angioscopy
この論文をさがす
抄録
The mortality rate due to rupture of aortic dissection and aortic aneurysm is approximately 90%. Acute aortic rupture can be fatal prior to hospitalization and has proven difficult to diagnose correctly or predict. The in-hospital mortality rate of ruptured aortic aneurysm ranges from 53 to 66%. Emergency surgical and endovascular treatments are the only options for ruptured aortic dissection and aortic aneurysm. No method of systematic early detection or inspection of vessel injury is available at the prevention stage. Regardless of the improvement in many imaging modalities, aortic diameter has remained a major criterion for recommending surgery in diagnosed patients. Previous reports have suggested a relationship between vulnerable plaque and atherosclerotic aortic aneurysm. Non-obstructive angioscopy is a new method for evaluating intimal injury over the whole aorta. It has been used to identify many advanced atherosclerotic plaques that were missed on traditional imaging modalities before aneurysm formation. Non-obstructive angioscopy has shown that atherosclerosis of the aorta begins before that of the coronary artery, which had been noted on autopsy “in vivo”. Strong or repetitive aortic injuries might cause sudden aortic disruption. Aortic atheroma is also a risk factor of stroke and perivascular embolism. Detecting aortic vulnerable atherosclerotic plaque on non-obstructive angioscopy may not only clarify the pathogenesis of acute aortic rupture and “aortogenic” thromboemboli and atheroemboli but also play a role in the pre-emptive medicine. (Circ J 2015; 79: 742–750)
収録刊行物
-
- Circulation Journal
-
Circulation Journal 79 (4), 742-750, 2015
一般社団法人 日本循環器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001205107422848
-
- NII論文ID
- 40020412213
- 130005130233
-
- NII書誌ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
-
- NDL書誌ID
- 026283685
-
- PubMed
- 25766407
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可