Effects of food enriched with egg yolk hydrolysate (bone peptide) on bone metabolism in orchidectomized dogs

DOI Web Site PubMed 参考文献14件
  • KOBAYASHI Toyokazu
    Laboratory of Veterinary Physiology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan
  • KOIE Hiroshi
    Laboratory of Veterinary Physiology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan
  • WATANABE Arisa
    Department of Animal Science, Teikyo University of Science, 2-2-1 Senjusakuragi, Adachi-ku, Tokyo 120-0045, Japan
  • INO Arisa
    Department of Animal Science, Teikyo University of Science, 2-2-1 Senjusakuragi, Adachi-ku, Tokyo 120-0045, Japan
  • WATABE Kazuya
    Pharma Foods International Co., LTD, 1-49 Goryo-Ohara, Nishikyo-ku, Kyoto 615-8245, Japan
  • KIM Mujo
    Pharma Foods International Co., LTD, 1-49 Goryo-Ohara, Nishikyo-ku, Kyoto 615-8245, Japan
  • KANAYAMA Kiichi
    Laboratory of Veterinary Physiology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan
  • OTSUJI Kazuya
    Department of Animal Science, Teikyo University of Science, 2-2-1 Senjusakuragi, Adachi-ku, Tokyo 120-0045, Japan

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We examined the effects of chicken egg hydrolysate (also known as “bone peptide” or BP) on bone metabolism in 5- to 8-month-old orchidectomized dogs. The bone formation marker serum bone alkaline phosphatase (BAP) and the bone resorption marker urine deoxypyridinoline (DPD) were used as indicators to measure changes in bone metabolism. The following results were observed that Serum BAP was higher in dogs fed BP-enriched food throughout the clinical investigation. Serum BAP was statistically significantly higher in dogs fed BP-enriched food than in dogs fed non-BP-enriched food at 2 months after orchidectomy. This suggests that BP promoted bone formation immediately after orchidectomy.

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