ABO Blood Type and Response of Activated Partial Thromboplastin Time to Dabigatran in Nonvalvular Atrial Fibrillation Patients
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- Suzuki Shinya
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Otsuka Takayuki
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Sagara Koichi
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Semba Hiroaki
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Kano Hiroto
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Matsuno Shunsuke
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Takai Hideaki
- Department of Cardiovascular Surgery, The Cardiovascular Institute
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- Kato Yuko
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Uejima Tokuhisa
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Oikawa Yuji
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Nagashima Kazuyuki
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Kirigaya Hajime
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Kunihara Takashi
- Department of Cardiovascular Surgery, The Cardiovascular Institute
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- Yajima Junji
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Sawada Hitoshi
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Aizawa Tadanori
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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- Yamashita Takeshi
- Department of Cardiovascular Medicine, The Cardiovascular Institute
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Background:The association between ABO blood type and the activated partial thromboplastin time (aPTT) under dabigatran therapy in nonvalvular atrial fibrillation (NVAF) patients is unclear.Methods and Results:Between 2011 March and 2015 May, data on ABO blood type and aPTT under dabigatran were obtained for 396 NVAF patients (baseline aPTT, 166). The prevalence of blood type O tended to increase or significantly increase according to baseline aPTT, aPTT under dabigatran, and their difference (∆aPTT) (P=0.054, 0.001, and 0.012, respectively).Conclusions:In these NVAF patients, a high aPTT value under dabigatran therapy was associated with blood type O. (Circ J 2015; 79: 2274–2277)
収録刊行物
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- Circulation Journal
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Circulation Journal 79 (10), 2274-2277, 2015
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680083468672
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- NII論文ID
- 130005099857
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 026750132
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- PubMed
- 26310875
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可