Award Accounts : The Chemical Society of Japan Award for Creative Work for 2014 : Development of Shelf-Stable Reagents for Fluoro-Functionalization Reactions

• Shibata Norio

  Department of Frontier Materials, Department of Nanopharmaceutical Sciences, Life Science and Applied Chemistry, Nagoya Institute of Technology

書誌事項

タイトル別名

• Development of Shelf-Stable Reagents for Fluoro-Functionalization Reactions

抄録

It is highly probable that the first impression that organic chemists would have of fluorine, F, is that it is “dangerous”. Elemental fluorine, F₂, is a gas that reacts with all elements quickly and violently. The oxidation power of F₂ is extraordinarily strong and even the noble gases such as Kr and Xe react with F₂ forming the corresponding fluorides. Fortunately, the receptiveness to fluorine chemistry by synthetic chemists has gradually changed in the late 20th century with the development of shelf-stable reagents for fluorination and trifluoromethylation reactions. In this account, I introduce our recent contributions to the development of shelf-stable reagents for the synthesis of organofluorine compounds. Electrophilic reagents for fluorination, mono-, di-, and trifluoromethylation, and trifluoromethylthiolation are discussed. Nucleophilic reagents for monofluoromethylation are also described including enantioselective reactions.

収録刊行物

• Bulletin of the Chemical Society of Japan

  Bulletin of the Chemical Society of Japan 89 (11), 1307-1320, 2016

  公益社団法人 日本化学会

キーワード

• General Chemistry

詳細情報

• CRID: 1390001204142494208
• NII論文ID: 130005316052
• NII書誌ID: AA00580132
• DOI: 10.1246/bcsj.20160223
• ISSN: 13480634
• ISSN: 00092673
• NDL書誌ID: 027719275
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027719275
• Web Site: https://academic.oup.com/bcsj/article-pdf/89/11/1307/56325629/bcsj.20160223.pdf
• 本文言語コード: en
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