A Triple-Electrode Based Dual-Biosensor System Utilizing Track-Etched Microporous Membrane Electrodes for the Simultaneous Determination of L-Lactate and D-Glucose
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- Mizuguchi Hitoshi
- Department of Applied Chemistry, Graduate School of Science and Technology, Tokushima University
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- Sasaki Keiko
- Graduate School of Science and Engineering, Yamagata University
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- Ichinose Hirokazu
- Graduate School of Science and Engineering, Yamagata University
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- Seino Shota
- Graduate School of Science and Engineering, Yamagata University
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- Sakurai Jun
- Graduate School of Science and Engineering, Yamagata University
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- Iiyama Masamitsu
- Nomura Micro Science Co., Ltd.
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- Kijima Tatsuro
- Graduate School of Science and Engineering, Yamagata University
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- Tachibana Kazuhiro
- Graduate School of Science and Engineering, Yamagata University
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- Nishina Tatsuo
- Graduate School of Science and Engineering, Yamagata University
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- Takayanagi Toshio
- Department of Applied Chemistry, Graduate School of Science and Technology, Tokushima University
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- Shida Junichi
- Graduate School of Science and Engineering, Yamagata University
Bibliographic Information
- Other Title
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- A Triple-Electrode Based Dual-Biosensor System Utilizing Track-Etched Microporous Membrane Electrodes for the Simultaneous Determination of <scp>l</scp>-Lactate and <scp>d</scp>-Glucose
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Abstract
<p>A new triple-electrode system was developed for the simultaneous determination of l-lactate and d-glucose by using track-etched microporous membrane electrodes, which enabled efficient electrolysis as electroactive substances passed through the electrode. The proposed biosensor was fabricated by alternate stacking of the electrodes and immobilized enzyme reactors along the flow direction of the sample solution. When the sample solution containing l-lactate and d-glucose flowed into the proposed biosensor, hydrogen peroxide was produced by each enzymatic reaction and detected individually by anodization at each detector-electrode positioned downstream of each enzyme reactor. The interfering substances, such as l-ascorbic acid and uric acid, were electrolyzed completely at the pre-reactor electrode that was positioned upstream of the enzyme reactors. As a result, the simultaneous detection of l-lactate and d-glucose was achieved with no other catalytic material such as peroxidase or an electron mediator in the presence of the interferents at physiological concentrations in human blood.</p>
Journal
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- Bulletin of the Chemical Society of Japan
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Bulletin of the Chemical Society of Japan 90 (11), 1211-1216, 2017
The Chemical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001204144024704
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- NII Article ID
- 130006201505
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- NII Book ID
- AA00580132
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- ISSN
- 13480634
- 00092673
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- NDL BIB ID
- 028640960
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed