Quantitative structure-activity analyses of diarylamine uncouplers 脱共役活性を示す置換ジアリールアミン類の定量的構造活性相関に関する研究

Access this Article

博士論文

論文目録 / (0001.jp2)
Contents / p1 (0004.jp2)
General Introduction / p1 (0006.jp2)
Chapter 1. Correlation Analyses for the Acid Dissociation Constants of Multi-Substituted Diarylamines / p4 (0008.jp2)
1-1 Introduction / p4 (0008.jp2)
1-2 Materials and Methods / p5 (0008.jp2)
1-3 Results and Correlation Analyses / p11 (0011.jp2)
1-4 Discussion / p29 (0020.jp2)
Chapter 2. Solvent Effects on the Acid Dissociation Constant of Diarylamines / p49 (0030.jp2)
2-1 Introduction / p49 (0030.jp2)
2-2 Materials and Methods / p49 (0030.jp2)
2-3 Results and Discussion / p52 (0032.jp2)
Chapter 3. Metabolic Decomposition of Diarylamine Uncouplers with Rat-Liver Mitochondria / p63 (0037.jp2)
3-1 Introduction / p63 (0037.jp2)
3-2 Materials and Methods / p64 (0038.jp2)
3-3 Results / p66 (0039.jp2)
3-4 Discussion / p72 (0042.jp2)
Chapter 4. Quantitative Structure-Activity Relationship (QSAR) of Uncoupling Activity of Diarylamines with Rat-Liver Mitochondria / p76 (0044.jp2)
4-1 Introduction / p76 (0044.jp2)
4-2 Materials and Methods / p77 (0044.jp2)
4-3 Results / p80 (0046.jp2)
4-4 Discussion / p84 (0048.jp2)
General Summary / p96 (0054.jp2)
References / p98 (0055.jp2)
Acknowledgments / p104 (0058.jp2)

1access