Cytochrome P-450s involved in calcium homeostasis vitamin D[3] 25-hydroxylase and 25-hydroxyvitamin D[3] 24-hydroxylase カルシウムホメオスタシスに関与するシトクロムP-450ビタミンD[3]25-水酸化酵素および25-ヒドロキシビタミンD[3]24-水酸化酵素
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著者
書誌事項
- タイトル
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Cytochrome P-450s involved in calcium homeostasis vitamin D[3] 25-hydroxylase and 25-hydroxyvitamin D[3] 24-hydroxylase
- タイトル別名
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カルシウムホメオスタシスに関与するシトクロムP-450ビタミンD[3]25-水酸化酵素および25-ヒドロキシビタミンD[3]24-水酸化酵素
- 著者名
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大山, 義彦
- 著者別名
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オオヤマ, ヨシヒコ
- 学位授与大学
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広島大学
- 取得学位
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理学博士
- 学位授与番号
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乙第2142号
- 学位授与年月日
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1991-03-18
注記・抄録
博士論文
目次
- Contents / p1 (0005.jp2)
- General Introduction and The Scope of The Thesis / p3 (0007.jp2)
- Chapter1 Multi-Functional Property of Rat Liver Mitochondrial Cytochrome P-450:Vitamin D₃ 25-Hydroxylase / p9 (0013.jp2)
- Summary / p10 (0014.jp2)
- Introduction / p11 (0015.jp2)
- Experimental Procedures / p14 (0018.jp2)
- Results / p17 (0021.jp2)
- Discussion / p19 (0023.jp2)
- References / p23 (0027.jp2)
- Figure & Table / p26 (0030.jp2)
- Chapter2 Purification and Characterization of a Cytochrome P-450 in Rat Kidney Mitochondria Catalyzing 24-Hydroxylation of 25-HIydroxyvitamin D₃ / p33 (0037.jp2)
- Summary / p34 (0038.jp2)
- Introduction / p36 (0040.jp2)
- Experimental Procedures / p38 (0042.jp2)
- Results / p45 (0049.jp2)
- Discussion / p50 (0054.jp2)
- References / p54 (0058.jp2)
- Figure & Table / p58 (0062.jp2)
- Chapter3 Cloning and Expression of cDNA Encoding 25-Hydroxyvitamin D₃ 24-Hydroxylase / p72 (0076.jp2)
- Summary / p73 (0077.jp2)
- Introduction / p74 (0078.jp2)
- Experimental Procedures / p75 (0079.jp2)
- Results & Discussion / p77 (0081.jp2)
- References / p80 (0084.jp2)
- Figure & Table / p82 (0086.jp2)
- Ring Transformation Equilibrium(Bond Switch)in the 5-(2-Aminovinyl)isothiazole System via Hypervalent Sulfurane.Synthesis,Structure Determination,and Kinetic Study / (0098.jp2)
- Alteration of Cholesterol Biosynthetic Pathways in the Skin of Mice Administered Polycvclic Aromatic Hydrocarbons¹ / p2555 (0108.jp2)
- purification and Characterization of Vitamin D 25-Hydroxylase from Rat Liver Mitochondria* / (0114.jp2)
- Purification and Characterization of 5β-Cholestane-3α,7α,12α-triol 27-Hydroxylase from Female Rat Liver Mitochondria / p18138 (0119.jp2)
- Cytochrome P-450:Biochemistry and Biophysics / (0124.jp2)
- Purification of 25-hydroxyvitamin D₃ 24-hydroxylase from rat kidney mitochondria / p405 (0129.jp2)
- Effect of chemical carcinogens on cholesterol biosynthetic pathways in the skin of mice / p1647 (0133.jp2)
- Unique property of liver mitochondrial P450 to catalyze the two physiologically important reactions involved in both cholesterol catabolism and vitamin D activation / p175 (0138.jp2)
- Cloning and expression of cDNA encoding 25-hydroxyvitamin D₃ 24-hydroxylase / p195 (0141.jp2)
- Multi-Functional Property of Rat Liver Mitochondrial Cytochrome P-450¹ / p389 (0145.jp2)