Functional characterization of the c-myb proto-oncogene product c-myb癌原遺伝子産物の機能解析

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著者

    • 中越, 英樹 ナカゴシ, ヒデキ

書誌事項

タイトル

Functional characterization of the c-myb proto-oncogene product

タイトル別名

c-myb癌原遺伝子産物の機能解析

著者名

中越, 英樹

著者別名

ナカゴシ, ヒデキ

学位授与大学

東京理科大学

取得学位

薬学博士

学位授与番号

甲第175号

学位授与年月日

1991-03-20

注記・抄録

博士論文

目次

  1. CONTENTS / p1 (0003.jp2)
  2. ABBREVIATIONS / p3 (0005.jp2)
  3. GENERAL INTRODUCTION / p4 (0006.jp2)
  4. MATERIALS AND METHODS / p9 (0011.jp2)
  5. CHAPTER I. Transcriptional trans-activation by the c-myb proto-oncogene / p19 (0021.jp2)
  6. INTRODUCTION / p19 (0021.jp2)
  7. RESULTS / p20 (0022.jp2)
  8. I-1. Stimulation of CAT gene expression by c-Myb / p20 (0022.jp2)
  9. I-2. Analysis of CAT RNA and copy number of the reporter plasmid after transfection / p22 (0024.jp2)
  10. I-3. Tandem repeats of the SV40 enhancer responsible for the c-Myb-induced trans-activation / p23 (0025.jp2)
  11. DISCUSSION / p30 (0032.jp2)
  12. CHAPTER II. Stimulation of transcription by binding of the c-myb proto-oncogenc product to the simian virus 40 enhancer / p31 (0033.jp2)
  13. INTRODUCTION / p31 (0033.jp2)
  14. RESULTS / p33 (0035.jp2)
  15. II-1. Sequence-specific DNA binding activity of the bacterially expressed c-Myb protein / (0035.jp2)
  16. II-2. Similarity of the binding sequences between native c-Myb protein and the bacterially expressed c-Myb protein / p39 (0041.jp2)
  17. II-3. MBS-I sequence responsible for c-Myb induced trans-activation / p45 (0047.jp2)
  18. DISCUSSION / p48 (0050.jp2)
  19. CHAPTER III. Transcriptional trans-repression by the c-myb proto-oncogenc product / p51 (0053.jp2)
  20. INTRODUCTION / p51 (0053.jp2)
  21. RESULTS / p52 (0054.jp2)
  22. III-1. SV-II sequence responsible for the c-Myb-induced trans-rcprcssion / p52 (0054.jp2)
  23. III-2. Sequence-specific binding of the bacterially expressed c-Myb protein to the MBS-II site / p53 (0055.jp2)
  24. III-3. Mutational analysis of SV-II sequence / p54 (0056.jp2)
  25. DISCUSSION / p60 (0062.jp2)
  26. CONCLUSIONS AND PERSPECTIVES / p62 (0064.jp2)
  27. ACKNOWLEDGEMENTS / p65 (0067.jp2)
  28. REFERENCES / p66 (0068.jp2)
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各種コード

  • NII論文ID(NAID)
    500000079181
  • NII著者ID(NRID)
    • 8000000079385
  • DOI(NDL)
  • NDL書誌ID
    • 000000243495
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
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