Studies on the protein phosphatases specific to phosphoserine and phosphothreonine ホスフォセリン及びホスフォスレオニンに特異的なプロテインホスファターゼに関する研究
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著者
書誌事項
- タイトル
-
Studies on the protein phosphatases specific to phosphoserine and phosphothreonine
- タイトル別名
-
ホスフォセリン及びホスフォスレオニンに特異的なプロテインホスファターゼに関する研究
- 著者名
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北川, 義徳
- 著者別名
-
キタガワ, ヨシノリ
- 学位授与大学
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神戸大学
- 取得学位
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理学博士
- 学位授与番号
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乙第1454号
- 学位授与年月日
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1990-09-28
注記・抄録
博士論文
目次
- CONTENTS / p1 (0004.jp2)
- CONTENTS / p1 (0004.jp2)
- LIST OF TABLES / p4 (0007.jp2)
- LIST OF FIGURES / p4 (0007.jp2)
- ACKNOWLEDGMENTS / p6 (0009.jp2)
- SUMMARY / p7 (0010.jp2)
- INTRODUCTION / p10 (0013.jp2)
- 1.Classification of Serine-Threonine Protein Phosphatases / p11 (0014.jp2)
- 2.Characteristics of Protein Phosphatases / p11 (0014.jp2)
- 3.Major Functions of Protein Phosphatases / p17 (0020.jp2)
- 4.Regulation of Protein phosphatase Activity / p20 (0023.jp2)
- MATERIALS AND METHODS / p24 (0027.jp2)
- 1.Phages,Plasmids and Bacterial Strains / p24 (0027.jp2)
- 2.Cell Lines and Culture Conditions / p24 (0027.jp2)
- 3.Determination of Peptide Sequence / p25 (0028.jp2)
- 4.Screening of cDNA Library / p25 (0028.jp2)
- 5.DNA Sequencing / p26 (0029.jp2)
- 6.Northern Blot Analysis / p26 (0029.jp2)
- 7.Southern Blot Analysis / p27 (0030.jp2)
- 8.Germ Cell Fractionation / p27 (0030.jp2)
- 9.Screening of Genomic Library / p27 (0030.jp2)
- 10.Primer Extension Analysis / p28 (0031.jp2)
- 11.Plasmid Construction for Chloramphenicol Acetyltransferase(CAT) Assay / p28 (0031.jp2)
- 12.DNA Transfection and CAT Assay / p29 (0032.jp2)
- 13.Measurement for PP-1 and PP-2A Activities / p29 (0032.jp2)
- RESULTS / p32 (0035.jp2)
- 1.Cloning the cDNA for the Catalytic Subunits of Rat PP-2A / p32 (0035.jp2)
- 2.Tissue Specific Expression of Serine-Threonine Protein Phosphatases / p38 (0041.jp2)
- 3.Expressions of Protein Phosphatase Genes in Malignant Cells / p46 (0049.jp2)
- 4.Expressions and Activities of Protein Phosphatases in Cell Proliferation / p51 (0054.jp2)
- 5.Analysis of the Promoter Region of the Gene for PP-2Aα / p62 (0065.jp2)
- DISCUSSION / p73 (0076.jp2)
- 1.Structure of the Catalytic Subunits of Serine-Threonine Protein Phosphatases / p73 (0076.jp2)
- 2.Tissue Specific Expressions of Protein Phosphatases and Their Possible Physiological Roles / p78 (0081.jp2)
- 3.Possible Involvements of Protein Phosphatases in Malignant Transformation / p83 (0086.jp2)
- 4.Regulation of PP-2Aα Gene Expression / p87 (0090.jp2)
- CONCLUSION / p90 (0093.jp2)
- REFERENCES / p91 (0094.jp2)