A clinical study of electrocochleography in Meniere's disease

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著者

    • 麻生, 伸 アソウ, シン

書誌事項

タイトル

A clinical study of electrocochleography in Meniere's disease

著者名

麻生, 伸

著者別名

アソウ, シン

学位授与大学

富山医科薬科大学

取得学位

医学博士

学位授与番号

乙第130号

学位授与年月日

1991-02-13

注記・抄録

博士論文

Electrocochleography (ECochG) of 168 ears with definite Meniere's disease was studied.The results were compared with recordings from 29 normal ears and 444 ears with other types of sensorineural hearing loss.It is shown that the SP/AP ratio is much more useful than SP amplitude for detecting endolymphatic hydrops.There was little difference in the mean values of SP/AP from those proposed by many other investigators; the mean values all being near 0.25.From 0.30 to 0.40 of SP/AP was considered adequate as the upper limit.Following intravenous administration of glycerol, a significant decrease in SP/AP was found in 21 Meniere's ears.However, there was no change of SP/AP after oral administration of glycerol and isosorbide.This difference may be due to the fact that a larger oral than intravenous administration is necessary to affect SP/AP.Although a postoperative decrease of 10% or more in SP/AP was observed in 5 patients, 10 patients followed up for 2 years or more after surgery did not show a statistically significant change of SP/AP and pure tone threshold.ECochG should be repeatedly recorded to be useful as a monitor for the presence of hydrops.It is discussed whether biochemical or mechanical changes in endolymph may cause a decrease in SP/AP after the use of dehydrating agents and endolymphatic sac surgery.

富山医科薬科大学・医学博士・乙第130号・麻生伸・1991/2/13

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各種コード

  • NII論文ID(NAID)
    500000079823
  • NII著者ID(NRID)
    • 8000000080028
  • DOI(NDL)
  • 本文言語コード
    • eng
  • NDL書誌ID
    • 000000244137
  • データ提供元
    • 機関リポジトリ
    • NDL-OPAC
    • NDLデジタルコレクション
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