Production of chiral intermediates for D-pantothenate and L-carnitine synthesis by microbial enzymes 微生物酵素によるD-パントテン酸およびL-カルニチン合成に有用な光学活性中間体の生産

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著者

    • 片岡, 道彦 カタオカ, ミチヒコ

書誌事項

タイトル

Production of chiral intermediates for D-pantothenate and L-carnitine synthesis by microbial enzymes

タイトル別名

微生物酵素によるD-パントテン酸およびL-カルニチン合成に有用な光学活性中間体の生産

著者名

片岡, 道彦

著者別名

カタオカ, ミチヒコ

学位授与大学

京都大学

取得学位

農学博士

学位授与番号

甲第4924号

学位授与年月日

1991-11-25

注記・抄録

博士論文

目次

  1. 論文目録 / (0001.jp2)
  2. CONTENTS / (0005.jp2)
  3. INTRODUCTION / p1 (0007.jp2)
  4. CHAPTER I Microbial Production of D-(-)-Pantoyl Lactone / p5 (0009.jp2)
  5. Section1 Ketopantoic Acid Reductase of Pseudomonas maltophilia 845: Purification, Characterization and Role in Pantothenate Biosynthesis / p5 (0009.jp2)
  6. Section2 Novel Enzymatic Production of D-(-)-Pantoyl Lactone through the Stereospecific Reduction of Ketopantoic Acid / p27 (0020.jp2)
  7. Section3 Purification and Characterization of a Novel FMN-Dependent Enzyme, Membrane-Bound L-(+)-Pantoyl Lactone Dehydrogenase,from Nocardia asteroides / p36 (0025.jp2)
  8. Section4 Stereospecific Conversion of a Racemic Pantoyl Lactone to D-(-)-Pantoyl Lactone through Microbial Oxidation and Reduction Reactions / p53 (0033.jp2)
  9. CHAPTER II Enzymatic Synthesis of D-(+)-Pantothenate Esters and D-(+)-Pantothenonitrile / p58 (0036.jp2)
  10. Section1 Stereospecific Reduction of Ethyl 2'-Ketopantothenate to Ethyl D-(+)-Pantothenate with Microbial Cells as a Catalyst / p58 (0036.jp2)
  11. Section2 Enzymatic Synthesis of Chiral Pantothenonitrile through Stereospecific Reduction of 2'-Ketopantothenonitrile / p63 (0038.jp2)
  12. Section3 A Novel NADPH-Dependent Carbonyl Reductase of Candida macedoniensis: Purification and Characterization / p67 (0040.jp2)
  13. CHAPTER III Production of Optically Active 4-Chloro-3-Oxobutanoate Esters by Microbial Aldehyde Reductase / p83 (0048.jp2)
  14. Section1 A Novel NADPH-Dependent Aldehyde Reductase, Catalyzing Asymmetric Reduction of β-Keto Acid Esters, from Sporobolomyces salmonicolor: Purification and Characterization / p83 (0048.jp2)
  15. Section2 Characterization of Aldehyde Reductase of Sporobolomyces salmonicolor / p88 (0051.jp2)
  16. Section3 Distribution and Immunological Characterization of Microbial Aldehyde Reductases / p99 (0056.jp2)
  17. Section4 Enzymatic Asymmetric Reduction of Ethyl 4-Chloro-3-Oxobutanoate to Optically Active Ethyl 4-Chloro-3-Hydroxybutanoate / p109 (0061.jp2)
  18. Section5 Stereoselective Reduction of Ethyl 4-Chloro-3-Oxobutanoate by a Microbial Aldehyde Reductase in an Organic Solvent-Water Diphasic System / p114 (0064.jp2)
  19. CONCLUSION / p123 (0068.jp2)
  20. ACKNOWLEDGMENTS / p127 (0070.jp2)
  21. REFERENCES / p128 (0071.jp2)
  22. PUBLICATIONS / p133 (0073.jp2)
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各種コード

  • NII論文ID(NAID)
    500000080836
  • NII著者ID(NRID)
    • 8000000081043
  • DOI(NDL)
  • NDL書誌ID
    • 000000245150
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
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