Production of chiral intermediates for D-pantothenate and L-carnitine synthesis by microbial enzymes 微生物酵素によるD-パントテン酸およびL-カルニチン合成に有用な光学活性中間体の生産
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著者
書誌事項
- タイトル
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Production of chiral intermediates for D-pantothenate and L-carnitine synthesis by microbial enzymes
- タイトル別名
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微生物酵素によるD-パントテン酸およびL-カルニチン合成に有用な光学活性中間体の生産
- 著者名
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片岡, 道彦
- 著者別名
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カタオカ, ミチヒコ
- 学位授与大学
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京都大学
- 取得学位
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農学博士
- 学位授与番号
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甲第4924号
- 学位授与年月日
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1991-11-25
注記・抄録
博士論文
目次
- 論文目録 / (0001.jp2)
- CONTENTS / (0005.jp2)
- INTRODUCTION / p1 (0007.jp2)
- CHAPTER I Microbial Production of D-(-)-Pantoyl Lactone / p5 (0009.jp2)
- Section1 Ketopantoic Acid Reductase of Pseudomonas maltophilia 845: Purification, Characterization and Role in Pantothenate Biosynthesis / p5 (0009.jp2)
- Section2 Novel Enzymatic Production of D-(-)-Pantoyl Lactone through the Stereospecific Reduction of Ketopantoic Acid / p27 (0020.jp2)
- Section3 Purification and Characterization of a Novel FMN-Dependent Enzyme, Membrane-Bound L-(+)-Pantoyl Lactone Dehydrogenase,from Nocardia asteroides / p36 (0025.jp2)
- Section4 Stereospecific Conversion of a Racemic Pantoyl Lactone to D-(-)-Pantoyl Lactone through Microbial Oxidation and Reduction Reactions / p53 (0033.jp2)
- CHAPTER II Enzymatic Synthesis of D-(+)-Pantothenate Esters and D-(+)-Pantothenonitrile / p58 (0036.jp2)
- Section1 Stereospecific Reduction of Ethyl 2'-Ketopantothenate to Ethyl D-(+)-Pantothenate with Microbial Cells as a Catalyst / p58 (0036.jp2)
- Section2 Enzymatic Synthesis of Chiral Pantothenonitrile through Stereospecific Reduction of 2'-Ketopantothenonitrile / p63 (0038.jp2)
- Section3 A Novel NADPH-Dependent Carbonyl Reductase of Candida macedoniensis: Purification and Characterization / p67 (0040.jp2)
- CHAPTER III Production of Optically Active 4-Chloro-3-Oxobutanoate Esters by Microbial Aldehyde Reductase / p83 (0048.jp2)
- Section1 A Novel NADPH-Dependent Aldehyde Reductase, Catalyzing Asymmetric Reduction of β-Keto Acid Esters, from Sporobolomyces salmonicolor: Purification and Characterization / p83 (0048.jp2)
- Section2 Characterization of Aldehyde Reductase of Sporobolomyces salmonicolor / p88 (0051.jp2)
- Section3 Distribution and Immunological Characterization of Microbial Aldehyde Reductases / p99 (0056.jp2)
- Section4 Enzymatic Asymmetric Reduction of Ethyl 4-Chloro-3-Oxobutanoate to Optically Active Ethyl 4-Chloro-3-Hydroxybutanoate / p109 (0061.jp2)
- Section5 Stereoselective Reduction of Ethyl 4-Chloro-3-Oxobutanoate by a Microbial Aldehyde Reductase in an Organic Solvent-Water Diphasic System / p114 (0064.jp2)
- CONCLUSION / p123 (0068.jp2)
- ACKNOWLEDGMENTS / p127 (0070.jp2)
- REFERENCES / p128 (0071.jp2)
- PUBLICATIONS / p133 (0073.jp2)