Syntheses and quantitative structure-activity analyses of inhibitors of 5-lipoxygenase and cyclooxygenase 5-リポキシゲナーゼおよびシクロオキシゲナーゼ阻害剤の合成と定量的構造活性相関に関する研究
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Bibliographic Information
- Title
-
Syntheses and quantitative structure-activity analyses of inhibitors of 5-lipoxygenase and cyclooxygenase
- Other Title
-
5-リポキシゲナーゼおよびシクロオキシゲナーゼ阻害剤の合成と定量的構造活性相関に関する研究
- Author
-
内藤, 洋一郎
- Author(Another name)
-
ナイトウ, ヨウイチロウ
- University
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京都大学
- Types of degree
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農学博士
- Grant ID
-
乙第7692号
- Degree year
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1991-11-25
Note and Description
博士論文
Table of Contents
- 論文目録 / (0001.jp2)
- Contents / (0004.jp2)
- General Introduction / p1 (0005.jp2)
- Chapter1 Preparation and Biological Activity of Catechol Derivatives Inhibiting 5-Lipoxygenase / p4 (0007.jp2)
- 1-1 Introduction / p4 (0007.jp2)
- 1-2 Syntheses β-Substituted 3,4-Dihydroxystyrenes(Series I) / p5 (0007.jp2)
- 1-3 Syntheses of 1-Substituted 3,4-Dihydroxybenzenes(Series II) / p8 (0009.jp2)
- 1-4 Syntheses of 6-Substituted 2,3-Dihydroxynaphthalenes(Series III) / p8 (0009.jp2)
- 1-5 Results and Discussion / p10 (0010.jp2)
- 1-6 Experimental Procedure / p13 (0011.jp2)
- Chapter2 Quantitative Structure-Activity Relationships of Catechol Derivatives Inhibiting 5-Lipoxygenase / p44 (0027.jp2)
- 2-1 Introduction / p44 (0027.jp2)
- 2-2 Experimental Procedure / p45 (0027.jp2)
- 2-3 Results and Discussion / p46 (0028.jp2)
- Chapter3 Preparation and Biological Activity of 2-[4-(Thiazol-2-yl)phenyl]propionic Acid Derivatives Inhibiting Cyclooxygenase / p64 (0037.jp2)
- 3-1 Introduction / p64 (0037.jp2)
- 3-2 Syntheses of 2-[3-Substituted-4-(thiazol-2-yl)phenyl] propionic Acids / p65 (0037.jp2)
- 3-3 Syntheses of 2-[3-Substituted-4-[4,5-disubstituted-thiazol-2-yl)phenyl]propionic Acids / p68 (0039.jp2)
- 3-4 Syntheses of 2-[4-(5-Substituted-thiazol-2-yl)phenyl]-propionic Acids / p71 (0040.jp2)
- 3-5 Results and Discussion / p72 (0041.jp2)
- 3-6 Experimental Procedures / p78 (0044.jp2)
- Chapter4 Quantitative Structure-Activity Relationships of 2-[4-(Thiazol-2-yl)phenyl]propionic Acid Derivatives Inhibiting Cyclooxygenase / p101 (0055.jp2)
- 4-1 Introduction / p101 (0055.jp2)
- 4-2 Experimental Procedure / p102 (0056.jp2)
- 4-3 Results and Discussion / p106 (0058.jp2)
- General Summary / p127 (0068.jp2)
- References and Notes / p130 (0070.jp2)
- Original Papers / p134 (0072.jp2)
- Acknowledgments / p135 (0072.jp2)