薬物速度論における一般理論の展開と最適化解析の応用

この論文をさがす

著者

    • 栗田, 昌裕, 1951- クリタ, マサヒロ

書誌事項

タイトル

薬物速度論における一般理論の展開と最適化解析の応用

著者名

栗田, 昌裕, 1951-

著者別名

クリタ, マサヒロ

学位授与大学

東京大学

取得学位

薬学博士

学位授与番号

乙第10086号

学位授与年月日

1991-03-08

注記・抄録

博士論文

目次

  1. Table of Contents / p3 (0005.jp2)
  2. Acknowledge / p2 (0004.jp2)
  3. Table of Contents / p3 (0005.jp2)
  4. General Introduction / p7 (0009.jp2)
  5. Construction of This Paper / p8 (0010.jp2)
  6. 〔Chaptor I〕 / 1-1 / (0011.jp2)
  7. The concept of "conformation" and the "combinatorial approach" for parameter estimation in multi-compartmental model systems / 1-1 / (0011.jp2)
  8. Summary / 1-2 / (0012.jp2)
  9. Introduction / 1-3 / (0013.jp2)
  10. Theory / 1-3 / (0013.jp2)
  11. Conclusion / 1-19 / (0029.jp2)
  12. References / 1-21 / (0031.jp2)
  13. Figure Legends / 1-22 / (0032.jp2)
  14. 〔Chaptor II〕 / 2-1 / (0042.jp2)
  15. On the pharmacokinetics of cyclical dosing: a general formulation using linearalgebraic theory of an approach permitting varying dose cycles and varying input sites / 2-1 / (0042.jp2)
  16. Summary / 2-2 / (0043.jp2)
  17. Introduction / 2-3 / (0044.jp2)
  18. Notations / 2-5 / (0046.jp2)
  19. Theory and Discussions / 2-7 / (0048.jp2)
  20. Concluding Remark / 2-26 / (0067.jp2)
  21. References / 2-30 / (0071.jp2)
  22. Appendices / 2-32 / (0073.jp2)
  23. 〔Chaptor III〕 / 3-1 / (0075.jp2)
  24. Generalized linear plateau principle in multi-compartmental models and linear monitoring systems during periodic dosing / 3-1 / (0075.jp2)
  25. Summary / 3-2 / (0076.jp2)
  26. Introduction / 3-3 / (0077.jp2)
  27. Theory and Discussions / 3-4 / (0078.jp2)
  28. Conclusing Remarks / 3-21 / (0096.jp2)
  29. Notations / 3-25 / (0100.jp2)
  30. References / 3-29 / (0104.jp2)
  31. Appendices / 3-31 / (0106.jp2)
  32. 〔Chaptor IV〕 / 4-1 / (0112.jp2)
  33. Optimization analysis of the clearance in heterogenously subdivided compartmental model systems / 4-1 / (0112.jp2)
  34. Summary / 4-2 / (0113.jp2)
  35. Introduction / 4-3 / (0114.jp2)
  36. Discussion / 4-21 / (0132.jp2)
  37. References / 4-26 / (0137.jp2)
  38. Appendices / 4-31 / (0142.jp2)
  39. Figure Legends / 4-34 / (0145.jp2)
  40. 〔Chaptor V〕 / 5-1 / (0150.jp2)
  41. Optimization analysis of moments in heterogenously subdivided compartmental model systems / 5-1 / (0150.jp2)
  42. Summary / 5-2 / (0151.jp2)
  43. Notations / 5-3 / (0152.jp2)
  44. Introduction / 5-4 / (0153.jp2)
  45. Theory / 5-7 / (0156.jp2)
  46. Discussion / 5-37 / (0186.jp2)
  47. Conclusion / 5-41 / (0190.jp2)
  48. References / 5-42 / (0191.jp2)
  49. Figure Legends / 5-48 / (0197.jp2)
  50. 〔Chaptor VI〕 / 6-1 / (0202.jp2)
  51. Optimization analysis of the effect of heterogenous distribution of diffusional barrier and intrinsic clearance on drug metabolism in the liver / 6-1 / (0202.jp2)
  52. Summary / 6-2 / (0203.jp2)
  53. Introduction / 6-3 / (0204.jp2)
  54. Discussion / 6-14 / (0215.jp2)
  55. Conclusion / 6-20 / (0221.jp2)
  56. References / 6-21 / (0222.jp2)
  57. Appendices / 6-24 / (0225.jp2)
  58. 〔Chaptor VII〕 / 7-1 / (0229.jp2)
  59. Geometric properties of the Linewerver-Burk plot for Michaelis-Menten kinetics in the case of multiple parallel non-identical elimination pathways for a single substrate / 7-1 / (0229.jp2)
  60. Summary / 7-2 / (0230.jp2)
  61. Introduction / 7-3 / (0231.jp2)
  62. Conclusion / 7-15 / (0243.jp2)
  63. References / 7-17 / (0245.jp2)
  64. Figure Legends / 7-18 / (0246.jp2)
  65. General Conclusion / 8-1 / (0249.jp2)
1アクセス

各種コード

  • NII論文ID(NAID)
    500000083413
  • NII著者ID(NRID)
    • 8000001012469
  • DOI(NDL)
  • NDL書誌ID
    • 000000247727
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
ページトップへ