Structural manipulation and functional regulation of hemoproteins by protein engineering 蛋白工学的手法によるヘム蛋白質の構造改変と機能制御

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著者

    • 足立, 伸一, 1964- アダチ, シンイチ

書誌事項

タイトル

Structural manipulation and functional regulation of hemoproteins by protein engineering

タイトル別名

蛋白工学的手法によるヘム蛋白質の構造改変と機能制御

著者名

足立, 伸一, 1964-

著者別名

アダチ, シンイチ

学位授与大学

京都大学

取得学位

工学博士

学位授与番号

甲第5111号

学位授与年月日

1992-03-23

注記・抄録

博士論文

目次

  1. 論文目録 / (0001.jp2)
  2. CONTENTS / p6 (0007.jp2)
  3. PREFACE / p1 (0004.jp2)
  4. ACKNOWLEDGMENTS / p3 (0005.jp2)
  5. LIST OF PUBLICATIONS / p5 (0006.jp2)
  6. CONTENTS / p6 (0007.jp2)
  7. I.GENERAL INTRODUCTION / p1 (0008.jp2)
  8. II.STRUCTURE AND FUNCTION OF SITE-DIRECTED MUTANTS OF MYOGLOBIN WITH MUTATIONS AT HEME PROXIMAL SITE AS MODELS FOR P-450, CHLOROPEROXIDASE, AND CATALASE / p13 (0014.jp2)
  9. 1.A Role of Proximal Ligand in Heme Proteins: Replacement of Proximal Histidine of Human Myoglobin to Cysteine and Tyrosine by Site-Directed Mutagenesis as Models for P-450, Chloroperoxidase, and Catalase / p14 (0015.jp2)
  10. 2.Alteration of Human Myoglobin Proximal Histidine to Cysteine or Tyrosine by Site-Directed Mutagenesis: Characterization and Their Catalytic Activities / p60 (0038.jp2)
  11. III.STRUCTURE AND LIGAND BINDING PROPERTIES OF VARIOUS MYOGLOBINS WITH MUTATIONS AT HEME DISTAL SITES / p73 (0044.jp2)
  12. 1.Structure and Ligand Binding Properties of Leucine 29(B10) Mutants of Human Myoglobin / p74 (0045.jp2)
  13. 2.Structure and Ligand Binding Properties of Lysine 45(CD3), Alanine 66(E9) and Threonine 67(E10) Mutants of Human Myoglobin / p105 (0060.jp2)
  14. 3.The Effects of Pressure on Oxygen and Carbon Monoxide Binding Kinetics for Myoglobin. A High-Pressure Laser Flash Photolysis Study / p117 (0066.jp2)
  15. IV.STRUCTURE AND LIGAND BINDING PROPERTIES OF CHEMICALLY MODIFIED MYOGLOBINS / p137 (0076.jp2)
  16. 1.The Effect of the Distal Histidine Modification (Cyanation) of Myoglobin on the Ligand Binding Kinetics and the Heme Environmental Structures / p138 (0077.jp2)
  17. 2.Modification of Distal Histidyl Imidazole in Myoglobin to N-Tetrazole Substituted Imidazole and Its Effect on the Ligand Binding Properties / p154 (0085.jp2)
  18. V.STRUCTURALLY ENGINEERED MYOGLOBINS AS MODELS FOR ELECTRON TRANSFER PROTEINS / p181 (0098.jp2)
  19. 1.Preparation of Recombinant Human Myoglobins Containing a Single Surface-Modifiable Histidine as Models for Electron Transfer Proteins / p182 (0099.jp2)
  20. VI.SUMMARY AND GENERAL CONCLUSIONS / p191 (0103.jp2)
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各種コード

  • NII論文ID(NAID)
    500000085979
  • NII著者ID(NRID)
    • 8000000979017
  • DOI(NDL)
  • NDL書誌ID
    • 000000250293
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
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