Studies on structure-function relationship of helical peptide pore-formers in membranes 膜中のヘリックスペプチドポア-形成体の構造-機能相関に関する研究
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著者
書誌事項
- タイトル
-
Studies on structure-function relationship of helical peptide pore-formers in membranes
- タイトル別名
-
膜中のヘリックスペプチドポア-形成体の構造-機能相関に関する研究
- 著者名
-
Masood Jelokhani-Niaraki
- 著者別名
-
マスード ジェロカーニ ニアラキ
- 学位授与大学
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佐賀大学
- 取得学位
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博士 (理学)
- 学位授与番号
-
甲第28号
- 学位授与年月日
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1995-03-22
注記・抄録
博士論文
目次
- Contents / p1 (0005.jp2)
- Acknowledgements / p4 (0008.jp2)
- Abbreviations / p5 (0009.jp2)
- Abstract / p7 (0011.jp2)
- Chapter1 / p1 (0013.jp2)
- Introduction / p1 (0013.jp2)
- 1-1 Peptide Models of Transmembrane Ion Channels / p2 (0014.jp2)
- 1-2 Instrumental Techniques / p17 (0029.jp2)
- 1-3 Aims and Perspectives of the Present Study / p22 (0034.jp2)
- Chapter2 / p26 (0038.jp2)
- Synthesis and Biological Activity of the Helical Peptide Aib Analogues of Linear Gramicidin / p26 (0038.jp2)
- 2-1 Synthesis / p27 (0039.jp2)
- 2-2 Biological Activity / p27 (0039.jp2)
- 2-3 Experimental / p29 (0041.jp2)
- Chapter3 / p42 (0054.jp2)
- Circular Dichroic Conformational Studies of Aib Analogues of Gramicidin in Organic, Aqueous and Phospholipid Vesicle Environments / p42 (0054.jp2)
- 3-1 Comparison Between Conformations of the Linear Gramicidin and Its Aib Analogues / p42 (0054.jp2)
- 3-2 Conformation of the Gramicidin B Aib Analogue in Aqueous and Organic Solvents, and Phospholipid Vesicles / p51 (0063.jp2)
- 3-3 Experimental / p63 (0075.jp2)
- Chapter4 / p69 (0081.jp2)
- Electrophysiological and Pore-Forming Characteristics of an Aib Analogue of Gramicidin / p69 (0081.jp2)
- 4-1 Functional Properties of GBA in a Phospholipid Bilayer System / p69 (0081.jp2)
- 4-2 Experimental / p80 (0092.jp2)
- Chapter5 / p82 (0094.jp2)
- Conclusion / p82 (0094.jp2)
- General Properties of Gramicidin Aib Analogues / p82 (0094.jp2)
- Solution and Vesicle Structures of the Aib Analogues / p84 (0096.jp2)
- Interaction of Trp with Membranes / p86 (0098.jp2)
- GBA Pores in Membranes / p88 (0100.jp2)
- Picturing the Pore-Forming Process of GBA / p91 (0103.jp2)
- Concluding Remarks / p95 (0107.jp2)
- Appendix I / p96 (0108.jp2)
- Symmetry and Chiroptical Activity of the Peptide Bond / p96 (0108.jp2)
- Appendix II / p99 (0111.jp2)
- Patch-Clamp Set-up / p99 (0111.jp2)
- Appendix III / p102 (0114.jp2)
- A.The Helix-Bundle Model / p102 (0114.jp2)
- B.Permeability of Ions Through Transmembrane Pores / p104 (0116.jp2)
- References / p105 (0117.jp2)
