Studies on calcium release channels from sarcoplasmic reticulum in planar bilayers 脂質平面膜による筋小胞体カルシウム放出チャネルの研究

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著者

    • 丁, 建 テイ, ケン

書誌事項

タイトル

Studies on calcium release channels from sarcoplasmic reticulum in planar bilayers

タイトル別名

脂質平面膜による筋小胞体カルシウム放出チャネルの研究

著者名

丁, 建

著者別名

テイ, ケン

学位授与大学

大阪大学

取得学位

博士 (理学)

学位授与番号

甲第5656号

学位授与年月日

1996-03-25

注記・抄録

博士論文

14401甲第05656号

博士(理学)

大阪大学

1996-03-25

12553

目次

  1. CONTENTS / (0003.jp2)
  2. Abbreviations / p1 (0005.jp2)
  3. Names of multiple conductance states of a Ca²⁺release channel / p2 (0006.jp2)
  4. Abstract / p3 (0007.jp2)
  5. Introduction / p5 (0009.jp2)
  6. Material and Method / p11 (0015.jp2)
  7. 1.Reagents / p11 (0015.jp2)
  8. 2.Preparation for HSR / p11 (0015.jp2)
  9. 3.Purification of RyR / p11 (0015.jp2)
  10. 4.Bilayer system and planar bilayer measurement / p12 (0016.jp2)
  11. 5.Protein concentration determination / p22 (0026.jp2)
  12. 6.Calculation of the free Ca²⁺concentration / p22 (0026.jp2)
  13. Result / p23 (0027.jp2)
  14. 1.Effect of ATP and ruthenium red to rapid fluctuation current / p23 (0027.jp2)
  15. 2.Slowly and rapidly fluctuating currents through RyR complex / p23 (0027.jp2)
  16. 3.Multiple conductance states in one small pore of RyR complex / p27 (0031.jp2)
  17. 4.Multiple conductance states in four small pores of RyR complex / p29 (0033.jp2)
  18. 5.Multiple conductance states of slow fluctuation current / p33 (0037.jp2)
  19. 6.DIDS effect to the current through RyR complex / p41 (0045.jp2)
  20. 7.Rapid fluctuation current with a high conductance state / p41 (0045.jp2)
  21. Discussion / p44 (0048.jp2)
  22. 1.Both rapid and slow fluctuation currents were the current through RyR complex / p44 (0048.jp2)
  23. 2.RyR complex has two different configurations / p44 (0048.jp2)
  24. 3.Slowly fluctuating current through RyR and the large pore in series / p45 (0049.jp2)
  25. 4.Pore fusion assumption and ryanodine induced sub-block states / p50 (0054.jp2)
  26. 5.Model of the states in the fused big pore / p54 (0058.jp2)
  27. 6.Multiple conductance states of RyR complex / p57 (0061.jp2)
  28. 7.High conductance states and glucose permeation / p59 (0063.jp2)
  29. 8.Ryanodine binding and ryanodine-induced responses / p61 (0065.jp2)
  30. 9.Open-lock behavior and DIDS effect / p62 (0066.jp2)
  31. 10.Rapid fluctuation current with large conductance(2500pS) / p64 (0068.jp2)
  32. 11.Selectivity of RyR / p64 (0068.jp2)
  33. References / p66 (0070.jp2)
  34. Acknowledgement / p72 (0076.jp2)
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各種コード

  • NII論文ID(NAID)
    500000130548
  • NII著者ID(NRID)
    • 8000000954296
  • DOI(NDL)
  • NDL書誌ID
    • 000000294862
  • データ提供元
    • 機関リポジトリ
    • NDL-OPAC
    • NDLデジタルコレクション
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